24/7 Helpline 800-950-LAWS (800-950-5297)

Actos (Pioglitazone)

Legal Options

The FDA took a closer look at the risk of bladder cancer amongst Actos users.

The agency evaluated the information from the first five years of a ten-year study on Actos, which was conducted by Takeda. By this point in the study, the results indicated that patients taking Actos were at a 40 percent increased risk of developing bladder cancer.

This information led to the Actos FDA warning, which was issued on June 15, 2011. This safety communication cautioned that patients who used Actos for more than a year, which includes the plaintiff, Stephen Tantillo, were at a much greater risk for bladder cancer. The FDA also ordered that the safety information for the drug be updated to reflect this risk.

Other countries have also taken note of the potentially life-threatening complications of Actos. On June 9, 2011, France announced that it was suspending all sales of medications containing pioglitazone. The announcement was based on a “statistically significant increase” in bladder cancer risk. Germany followed suit the very next day.

Lawsuits worldwide claim that Takeda, the Actos manufacturer, failed to warn consumers of known Actos side effects. Plaintiffs seek compensation for pain and suffering, lost wages, medical expenses, and other damages.

Studies Reveal Actos Bladder Cancer Risks

Some Actos plaintiffs claim that Takeda failed to disclose knowledge of potential Actos side effects. They reference a Takeda study conducted before FDA approval in 1999, which showed that lab rats taking clinical doses of Actos developed tumors. In 2005, the three-year PROactive study produced additional warnings regarding Actos bladder cancer. During the study, patients taking the diabetes drug displayed a higher risk of Actos bladder cancer than patients taking comparable medications.

People whom have been injured by Actos do have legal options

If you are a patient for whom Actos was prescribed, and after having followed the instructions of your physician you have found yourself with a diagnosis of bladder cancer, you do have options. The obvious first step that you should take is seeing a medical specialist and getting your condition taken care of. But treatment of bladder cancer is expensive, and can have a dramatic effect on your lifestyle.

You may not be able to continue working or taking care of your family, and may need to hire somebody to assist you. When a drug manufacturer puts patients’ and well-being at risk, the American legal system has remedies available. These include:

  • Mass Torts and Multi District Litigation: A mass tort is when a group of plaintiffs file their legal proceedings in a state court, while a multi district litigation (MDL) is held in a federal court.
  • Class Action Lawsuit: In a class-action lawsuit, plaintiffs with similar injuries all combine into one single lawsuit.
  • Individual lawsuits: In an individual lawsuit, the injured party sues the drug manufacturer directly both for the expenses that they have incurred as a result of their actions and for punitive damages.


Our firm works on a contingency basis which means you will not be asked to pay any money out of pocket.

This process will be very easy. Please feel free to answer all questions honestly as your information is confidential.

This process will be very easy. Please feel free to answer all questions honestly as your information is confidential.

Free Case Evaluation

Common Actos Side Effects

Some side effects of Actos are severe enough that they require immediate medical attention, while others do not. Some might be related to things like age, weight, gender and overall health. In addition, ethnicity and race may play a role in side effects.

  • Upper respiratory infection (similar to the common cold)
  • Headache
  • Sinus infection or sinus irritation
  • General ill feeling
  • Muscle pain
  • Tooth pain and problems
  • Sore throat
  • Allergic reactions such as skin rashes, hives, itching or swelling of the face, lips or tongue
  • Fever, chills
  • Unusual fatigue
Severe Actos Side Effects Include:
  • Bladder cancer
  • Congestive heart failure
  • Bone fractures
  • Lactic acidosis

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

© 2012 USDrugAlert.com, all rights reserved. Sponsored by Goza | Honnold, L.L.C.